程序性细胞死亡和疾病研究组

Laboratory of Programmed Cell Death and Diseases

(1) Fang Wang, Kaiying Li, Wensheng Wang , Jiang Hui, Jiangping He , Jin Cai, Wenqing Ren, Yaxing Zhao, Qianqian Song, Yuan He, Yanlei Ma, Xiaona Feng, Yue Liu , Jianqiang Yu, Jitkaew Siriporn, Dan Ma, Zhenyu Cai, Sensing of endogenous retroviruses-derived RNA by ZBP1 triggers PANoptosis in DNA damage and contributes to toxic side effects of chemotherapy, Cell Death & Disease, 2024 Oct 27;15(10):779. doi: 10.1038/s41419-024-07175-7. https://www.nature.com/articles/s41419-024-07175-7

(2) Yaxing Zhao, Qingsong Wang, Jing Zhu, Jin Cai, Xiaona Feng, Qianqian Song, Hui Jiang, Wenqing Ren, Yuan He, Ping Wang, Du Feng, Jianqiang Yu, Yue Liu, Qihui Wu, Jitkaew Siriporn, Zhenyu Cai, Identification of KW-2449 as a dual inhibitor of ferroptosis and necroptosis reveals that autophagy is a targetable pathway for necroptosis inhibitors to prevent ferroptosis, Cell Death & Disease, 2024 Oct 21;15(10):764. doi: 10.1038/s41419-024-07157-9. https://www.nature.com/articles/s41419-024-07157-9

(3) Yuan He, Tingting Yang, Jiao Li, Kaiying Li, Chunlin Zhuang, Meng Zhang, Ran Li, Yaxing Zhao, Qianqian Song, Mengyuan Jiang, Shuichun Mao, Xin-gang Song, Yufeng Guo, Xuran Li, Fei Tan, Siriporn Jitkaew, Wen Zhang, Zhenyu Cai,Identification of a marine-derived sesquiterpenoid compound, Cpd-8, that inhibits TNF-induced cell death by blocking complex II assembly,Br J Pharmacol., 2024 Aug;181(15):2443-2458. doi: 10.1111/bph.16364.  https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16364

(4) Yingbo Zhou , Zhangtao Cai , Yijia Zhai , Jintao Yu , Qiujing He, Yuan He , Siriporn Jitkaew , Zhenyu Cai, Necroptosis inhibitors: mechanisms of action and therapeutic potential, Apoptosis. 2024 Feb;29(1-2):22-44. doi: 10.1007/s10495-023-01905-6. https://link.springer.com/article/10.1007/s10495-023-01905-6

(5) Qingsong Wang, Fan Yang, Kun Duo, Yue Liu, Jianqiang Yu, Qihui Wu, Zhenyu Cai, The Role of Necroptosis in Cerebral Ischemic Stroke, Mol Neurobiol. 2024 Jul;61(7):3882-3898. doi: 10.1007/s12035-023-03728-7. https://link.springer.com/article/10.1007/s12035-023-03728-7
(6) Xiaobing Lan, Qing Wang, Yue Liu, Qing You, Wei Wei, Chunhao Zhu, Dongmei Hai, Zhenyu Cai, Jianqiang Yu, Jian Zhang, Ning Liu, Isoliquiritigenin alleviates cerebral ischemia-reperfusion injury by reducing oxidative stress and ameliorating mitochondrial dysfunction via activating the Nrf2 pathway, Redox Biol. 2024 Oct 22:77:103406. doi: 10.1016/j.redox.2024.103406. https://www.sciencedirect.com/science/article/pii/S2213231724003847?via%3Dihub

(7)  Yanhong Wang , Xinyu Mang , Danni Li , Zhao Wang , Yiliang Chen , Zhenyu Cai , Fei Tan, Cold atmospheric plasma sensitizes head and neck cancer to chemotherapy and immune checkpoint blockade therapy, Redox Biol. 2024 Feb:69:102991. doi: 10.1016/j.redox.2023.102991. https://www.sciencedirect.com/science/article/pii/S2213231723003920?via%3Dihub

(8) Jiaxi Chen, Jieping Zhang, Lijuan Cai, Li Guo, Zhenyu Cai, Hua Han, Wen Zhang, Cholestane-3β,5α,6β-triol Induces Multiple Cell Death in A549 Cells via ER Stress and Autophagy Activation, Mar Drugs. 2024 Apr 13;22(4):174. doi: 10.3390/md22040174. https://www.mdpi.com/1660-3397/22/4/174

 


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