程序性细胞死亡和疾病研究组

Laboratory of Programmed Cell Death and Diseases

       1   Qin X, Ma D, Tan Y#, Wang H#, Cai Z#. The role of necroptosis in cancer: a double-edged sword? 2019, Biochim Biophys Acta Rev Cancer, 1871:259-266. (#, Correspondence author) (Review) IF:8.220

        2     Chen X, Zhuang C†,#, Ren Y, Zhang H, Qin X, Hu L, Fu J, Miao Z, Chai Y, Liu Z, Cai Z#, Wang H# , Identification of TAK-632 and its analogues as potent inhibitors of necroptosis by targeting RIPK1 and RIPK3, 2019, Br J Pharmacol, 176(12):2095-2108, (#, Correspondence author; †, equal contribution)  IF: 6.810

        3     Zhang H, Xu L, Qin X, Chen X, Cong H, Hu L, Miao Z, Zhang W#, Cai Z#, Zhuang C#. TAK-632 Analogues as Novel Necroptosis Inhibitors Selectively Targeting RIPK3: Synthesis, Structure-Activity Relationships and In Vivo Efficacy, 2019, J Med Chem, 62(14):6665-6681 (#, Correspondence author; †, equal contribution)  (Cover Story) IF: 6.253

        4     Pan P, Cai Z, Zhuang C, Chen X, Chai Y. Methodology of drug screening and target identification for new  necroptosis inhibitors, 2019, J Pharm Anal, 9(2):71-76. (Review) 

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