程序性细胞死亡和疾病研究组

Laboratory of Programmed Cell Death and Diseases


1     Cai Z, Zhang A, Choksi S, Li W, Li T, Zhang X, and Liu Z. Activation of cell surface proteases promotes necroptosis, inflammation and cell migration. 2016, Cell Research, 26(8):886-900. IF: 15.393 

2     Cai Z, Liu Z. Execution of RIPK3-regulated necrosis. 2014, Molecular & Cellular Oncology, 1:2, e960759. (Review)

3     Cai Z, Jitkaew S, Zhao J, Chiang H, Choksi S, Liu J, Ward E, Wu L, Liu Z. Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis. Nat Cell Biol. 2014; 16(1):55-65. (†, equal contribution) (ESI Highly Cited Paper) IF: 19.064

4     Zhao J, Jitkaew S, Cai Z, Choksi S, Li Q, Luo J, Liu ZG. Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis. Proc Natl Acad Sci U S A. 2012; 109(14):5322-7. (, equal contribution) (ESI Highly Cited Paper) IF:9.504

5     Shi Z, Cai Z, Yu J, Zhang T, Zhao S, Smeds E, Zhang Q, Wang F, Zhao C, Fu S, Ghosh S, Zhang D. Toll-like receptor 11 (TLR11) prevents Salmonella penetration into the murine Peyer patches. J Biol Chem. 2012; 287(52):43417-23. IF: 4.011

6     Cai Z, Sancheza A, Shi Z, Zhang T, Liu M, Zhang D. Activation of Toll-Like receptor 5 on breast cancer cells by flagellin suppresses cell proliferation and tumor Growth. Cancer Res. 2011; 71(7):2466-75. IF: 9.130

7     Shi Z, Cai Z, Sancheza A, Zhang T, Wen S, Wang J, Yang J, Fu S, Zhang D. A Novel Toll-like receptor that recognizes vesicular stomatitis virus. J Biol Chem. 2011; 286(6):4517-24. IF: 4.011

8     Cai Z, Shi Z, Sanchez A, Zhang T, Liu M, Yang J, Wang F, Zhang D. Transcriptional regulation of TLR11 gene expression in epithelial cells. J Biol Chem. 2009; 284(48):33088-96. IF: 4.011

9     Shi Z, Cai Z, Wen S, Chen C, Gendron C, Sanchez A, Patterson K, Fu S, Yang J,  Wildman D, Finnell RH, Zhang D Transcriptional Regulation of the novel Toll-like receptor Tlr13. J Biol Chem. 2009; 284(31):20540-7. IF: 4.011

10   Cai Z, Zhang D. Toll-like receptor and cancer. Int J Genet. 2008; 31(4):275-281.

11   Cai Z, Wang Y, Yu W, Xiao J, Li Y, Liu L, Zhu C, Tan K, Deng Y, Yuan W, Liu M, Wu X. hnulp1, a bHLH  proteinwith a novel DUF654 domain, inhibits transcriptional activity of Serum Response Factor. Biochem Biophys Res Commun. 2006; 343(3):973-81. IF: 2.559

12   Ou Y, Wang S, Cai Z, Wang Y, Wang C, Li Y, Li F, Yuan W, Liu B, Wu X, Liu M. ZNF328, a novel human zinc-finger protein, suppresses transcriptional activities of SRE and AP-1. Biochem Biophys Res Commun. 2005; 333(3):1034-44 2. IF: 2.559

13   Wang Y, Li Y, Zeng W, Zhu C, Xiao J, Yuan W, Wang Y, Cai Z, Zhou J, Liu M, Wu X. IXL, a new subunit of the mammalian Mediator complex, functions as a transcriptional suppressor. Biochem Biophys Res Commun. 2004; 325(4):1330-8. IF: 2.559

14   蔡振宇. 第7章“心肌-内皮信号转导” ,《心脏发育研究》,湖南科学出版社, ISBN: 7-5357-3898-2 ,2004年2月,

15   蔡振宇, 袁婺洲, 吴秀山. 心肌-内皮信号途径在心脏发育中的作用, 2003, 生命科学研究. Vol. 7 No. 2 (Suppl.)


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