干细胞生理及疾病治疗研究组

Laboratory of Stem Cell Physiology and Disease Therapy

1.

Fangce Wang#,Zheng Li#,Jie Zhou, Guangming Wang,Wenjun zhang*,Jun Xu *Aibin Liang* .SIRT1 regulates the phosphorylation and degradation of P27 by deacetylating CDK2 to promote T-cell acute lymphoblastic leukemia progression. J. Exp. Clin. Cancer Res 2021 Aug 18;40(1):259 (*Corresponding author)


Zheng Li#,Fangce Wang#, Xiaoxue Tian, Jun Long, Bin Ling, Wenjun zhang*,Jun Xu *Aibin Liang*. HCK maintains the self-renewal of leukaemia stem cells via CDK6 in AML. J. Exp. Clin. Cancer Res 2021 Jun 24;40(1):210 (*Corresponding author)


Min-Min Lou#, Xiao-Qiang Tang#,Guang-Ming Wang#, Jia He,Fang Luo,Ming-Feng Guan,Fei Wang,Huan Zou,Jun-Ying Wang,Qun Zhang,Ming-Jian Xu,Qi-Li Shi,Li-Bing Shen,Guo-Ming Ma,Yi Wu,Yao-Yang Zhang,Ai-bin Liang,Ting-Hua Wang,Liu-Lin Xiong,Jian Wang*,Jun Xu* ,Wen-Yuan Wang* Long noncoding RNA BS-DRL1 modulates DNA damage response and genome stability in the central nervous systemby interacting with HMGB1.Nat Commun 2021 Jul 1;12(1):4075 (*Corresponding author)


Chiqi Chen#, Xiaoxin Hao#, Xiaoyun Lai#, Hongfang Shao#, Jun Zhu#, Dan Huang, Hao Gu, Tinghua Zhang, Zhuo Yu, Li Xie, Ligen Liu, Xiaocui Zhang, Yi Yang, Jun Xu*, Yuzheng Zhao*, Zhigang Lu*, Junke Zheng*. Oxidative phosphorylation enhances the leukemogenic capacity and resistance to chemotherapy of B-cell acute lymphoblastic leukemia. Science Advance 2021 Mar 10;7(11):eabd6280 (accepted) (*Corresponding author)


Qiande Hu*, Liang Zhu, Yuan Lia, Jianjun Zhou* , Jun Xu* . bACTA1 is inhibited by PAX3-FOXO1 through RhoA-MKL1-SRF signaling pathway and impairs cell proliferation, migration and tumor growth in Alveolar Rhabdomyosarcoma Cell & Bio 2021 Jan 28;11(1):25  (*Corresponding author)

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