Ø Linlin Zhou, Yuwei Wang, Yu Liu, Feipeng Zhu, Ge Gao, Chengjie Li, Pu Ai, Jingying Xu, Junxin Wang, Long Guo, Virginia Man-Yee Lee, Jianjun Chen, Jialin Zheng, Qihui Wu*. Dynein-dependent endo-lysosomal degradation drives Lewy body disorders accompanied by Aβ pathology. Advanced Science. 2025. Accepted. (* Corresponding author)

Ø Yihan Liu, Shengyang Fu, Yan He, Xinwei Huang, Huikang Xie, Leyan Chen, Qihui Wu *, Jialin C. Zheng *, Weijun Cao *, Antioxidative ceria nanoparticles protect acute lung injury-induced cognitive and emotional dysfunctions in mice. Chemical Engineering Journal. Available online 25 May 2025, 164147. https://doi.org/10.1016/j.cej.2025.164147 (* Corresponding author)

Ø Xiaoliang Fang†, Yi Zhong†, Rui Zheng†, Qihui Wu†, Yu Liu, Dexin Zhang, Yuwei Wang, Wubing Ding, Kaiyuan Wang, Fengbo Zhong, Kai Lin, Xiaohui Yao, Qingxun Hu, Xiaofei Li, Guofeng Xu , Na Liu , Jing Nie , Dali Li , Hongquan Geng *, Yuting Guan *，PPDPF preserves integrity of proximal tubule by modulating NMNAT activity in chronic kidney diseases，2025, Science Advances. https://www.science.org/doi/pdf/10.1126/sciadv.adr8648 († Co-first author)

Ø Weixian Kong, Yu Liu, Pu Ai, Yong Bi, Chaoguang Wei, Xiaoyang Guo, Zhenyu Cai, Ge Gao, Peng Hu, Jialin Zheng, Jianhui Liu, Minfeng Huo, Yuting Guan & Qihui Wu#, Genetically modified E. Coli secreting melanin (E.melanin) activates the astrocytic PSAP-GPR37L1 pathway and mitigates the pathogenesis of Parkinson’s disease. J Nanobiotechnol 22, 690 (2024). https://doi.org/10.1186/s12951-024-02955-x (# Corresponding author)

Ø Yaxing Zhao #, Qingsong Wang # , Jing Zhu #, Jin Cai, Xiaona Feng, Qianqian Song, Hui Jian, Wenqing Ren, Yuan He, Ping Wang, Du Feng, Jianqiang Yu, Yue Liu, Qihui Wu, Siriporn Jitkaew, Zhenyu Cai. Identification of KW-2449 as a dual inhibitor of ferroptosis and necroptosis reveals that autophagy is a targetable pathway for necroptosis inhibitors to prevent ferroptosis. Cell Death Dis. 2024 Oct 21;15(10):764.  doi: 10.1038/s41419-024-07157-9.

Ø  Wang Q, Yang F, Duo K, Liu Y, Yu J, Wu Q, Cai Z. The Role of Necroptosis in Cerebral Ischemic Stroke. Mol Neurobiol. 2024 Jul;61(7):3882-3898. doi: 10.1007/s12035-023-03728-7. Epub 2023 Dec 1. PMID: 38038880

Ø  Su J, Pan Y, Zhong F, Zhong Y, Huang J, Liu S, Wang K, Lin K, Gu X, Li D, Wu Q, Geng H, Guan Y, Xu G. Mitochondrial SLC3A1 regulates sexual dimorphism in cystinuria. Genes Dis. 2024 Nov 29;12(3):101472. doi: 10.1016/j.gendis.2024.101472. eCollection 2025 May. PMID: 40110490 
 
Ø  Jiale Han, Yihan Liu, Xiaoyang Guo, Ge Gao, Qihui Wu#, Research Trends in the Comorbidity Between Periodontitis and Neurodegenerative Diseases. Int Dent J. 2024 Aug 12:S0020-6539(24)01405-9.  doi: 10.1016/j.identj.2024.07.1212. Online ahead of print. (# Corresponding author)（本科生为第一作者）
 
Ø  Ke Su, Yu Ma, Mingshan Zhou, Yihan Liu, Chengjie Li, Yonghui Jiang, Qihui Wu#, Gang Peng#, Yi Wang#, Shaohua Fan#. De novo missense variants of UNC13A are implicated in epileptic encephalopathies and neurodevelopmental disorders. Genes & Diseases. Available online 6 May 2024, 101315.  https://doi.org/10.1016/j.gendis.2024.101315 (# Corresponding author)

Ø Chenhui Ji, Yalin Tang, Yanyan Zhang, Xiaoyan Huang, Congcong Li, Yuhong Yang, Qihui Wu, Xiaohuan Xia, Qingyuan Cai, Xin-Rui Qi, Jialin C Zheng. Glutaminase 1 deficiency confined in forebrain neurons causes autism spectrum disorder-like behaviors. Cell Rep. 2023 Jul 25;42(7):112712.  doi: 10.1016/j.celrep.2023.112712.  Epub 2023 Jun 28.

 
Ø  Bassil F, Meymand E, Brown H, Xu H, Cox T, Pattabhiraman S, Maghames C, Wu Q, Zhang B, Trojanowski J, Lee M. α-Synuclein modulates tau spreading in mouse brains. J Exp Med. 2021 Jan 4;218(1):e20192193. doi: 10.1084/jem.20192193.  

Ø  Jiang J, Liu Y, Wu Q#. Revisit the Cellular Transmission and Emerging Techniques in Understanding the Mechanisms of Proteinopathies. Front Neurosci. 2021 Nov 18;15:781722. doi: 10.3389/fnins.2021.781722.eCollection 2021. (# Corresponding author) 

Ø  Wu Q, Shaik M, Meymand E, Zhang B, Luk K, Trojanowski JQ, Lee VM. Neuronal activity modulates alpha‐synuclein aggregation and spreading in organotypic brain slice cultures and in vivo. Acta Neuropathol. 2020 Oct 6. doi: 10.1007/s00401-020-02227-6. Online ahead of print. 
 
Ø  Wu Q, Takano H, Riddle DM, Trojanowski JQ, Coulter DA, Lee VM. α-Synuclein (αSyn) Preformed Fibrils Induce Endogenous αSyn Aggregation, Compromise Synaptic Activity and Enhance Synapse Loss in Cultured Excitatory Hippocampal Neurons. J Neurosci. 2019 Jun 26;39(26):5080-5094.
 
Ø  Zhang Q*, Liu B*, Wu Q*, Liu B, Li Y, Sun S, Wang Y, Wu X, Chai Z, Jiang X, Liu X, Hu M, Wang Y, Yang Y, Wang L, Kang X, Xiong Y, Zhou Y, Chen X, Zheng L, Zhang B, Wang C, Zhu F, Zhou Z. Differential Co-release of Two Neurotransmitters from a Vesicle Fusion Pore in Mammalian Adrenal Chromaffin Cells. Neuron. 2019 Apr 3;102(1):173-183.e4. (* Co-first author)
 
Ø  Wu Q*, Zhang Q*, Liu B, Li Y, Wu X, Kuo S, Zheng L, Wang C, Zhu F, Zhou Z. Dynamin 1 Restrains Vesicular Release to a Subquantal Mode in Mammalian Adrenal Chromaffin Cells. J Neurosci. 2019 Jan 9;39(2):199-211. 
 
Ø  Wang Y*, Wu Q*, Hu M, Liu B, Chai Z, Huang R, Wang Y, Xu H, Zhou L, Zheng L, Wang C, Zhou Z. Ligand- and voltage-gated Ca2+ channels differentially regulate the mode of vesicular neuropeptide release in mammalian sensory neurons. Sci Signal. 2017 Jun 20;10(484). (* Co-first author, Front Cover).
 
Highlighted in Science (Ferrarelli LK, 2017, Kiss-and-run or a full commitment? 356(6344):1243-1245. doi: 10.1126/science.356.6344.1243-p). 
 
Ø  Kuo S*, Wu Q*, Liu B*, Xie Z, Wu X, Shang S, Zhang X, Zhou Z. Importing, caring, breeding, genotyping, and phenotyping a genetic mouse in a Chinese university. J Mol Neurosci. 2014 Jul;53(3):487-92. (* Co-first author)
 
Ø  Gibbons G, Kim SJ, Wu Q, Riddle DM, Leight SN, Changolkar L, Xu H, Meymand ES, O'Reilly M, Zhang B, Brunden KR, Trojanowski JQ, Lee VM.  Conformation-selective tau monoclonal antibodies inhibit tau pathology in primary neurons and a mouse model of Alzheimer's disease. Molecular Neurodegeneration. 2020 Nov 4;15(1):64. doi: 10.1186/s13024-020-00404-5.
 
Ø  Zhang Q, Liu B, Li Y, Yin L, Younus M, Jiang X, Lin Z, Sun S, Huang R, Liu B, Wu Q, Zhu F, Zhou Z. Regulating quantal size of neurotransmitter release through a GPCR voltage sensor. Proc Natl Acad Sci U S A. 2020 Oct 27;117(43):26985-26995. doi: 10.1073/pnas.2005274117. Epub 2020 Oct 12. 
 
Ø  Wang C, Kang X, Zhou L, Chai Z, Wu Q, Huang R, Xu H, Hu M, Sun X, Sun S, Li J, Jiao R, Zuo P, Zheng L, Yue Z, Zhou Z. Synaptotagmin-11 is a critical mediator of parkin-linked neurotoxicity and Parkinson's disease-like pathology. Nat Commun. 2018 Jan 8;9(1):81.
 
Ø  Chai Z, Wang C, Huang R, Wang Y, Zhang X, Wu Q, Wang Y, Wu X, Zheng L, Zhang C, Guo W, Xiong W, Ding J, Zhu F, Zhou Z. CaV2.2 Gates Calcium-Independent but Voltage-Dependent Secretion in Mammalian Sensory Neurons. Neuron. 2017 Dec 20;96(6):1317-1326.e4. 
 
Ø  Zhu F, Wu Q, Li J, Grycel K, Liu B, Sun X, Zhou L, Jiao R, Song R, Khan YM, Wang Q, Wang L, Xu Y, Li J, Zhang B, Zhou Z. A single dose of cocaine potentiates glutamatergic synaptic transmission onto locus coeruleus neurons. Cell Calcium. 2017 Nov;67:11-20. 
 
Ø  Shang S, Zhu F, Liu B, Chai Z, Wu Q, Hu M, Wang Y, Huang R, Zhang X, Wu X, Sun L, Wang Y, Wang L, Xu H, Teng S, Liu B, Zheng L, Zhang C, Zhang F, Feng X, Zhu D, Wang C, Liu T, Zhu MX, Zhou Z. Intracellular TRPA1 mediates Ca2+ release from lysosomes in dorsal root ganglion neurons. J Cell Biol. 2016 Nov 7;215(3):369-381. 
 
Ø  Wang C, Wang Y, Hu M, Chai Z, Wu Q, Huang R, Han W, Zhang CX, Zhou Z. Synaptotagmin-11 inhibits clathrin-mediated and bulk endocytosis. EMBO Rep.2016 Jan;17(1):47-63.
 
Ø  Xu H, Zuo P, Wang S, Zhou L, Sun X, Hu M, Liu B, Wu Q, Dou H, Liu B, Zhu F, Teng S, Zhang X, Wang L, Li Q, Jin M, Kang X, Xiong W, Wang C, Zhou Z. Striatal dopamine release in a schizophrenia mouse model measured by electrochemical amperometry in vivo. Analyst. 2015 Jun 7;140(11):3840-5. 
 
Ø  Dou H, Wang C, Wu X, Yao L, Zhang X, Teng S, Xu H, Liu B, Wu Q, Zhang Q, Hu M, Wang Y, Wang L, Wu Y, Shang S, Kang X, Zheng L, Zhang J, Raoux M, Lang J, Li Q, Su J, Yu X, Chen L, Zhou Z. Calcium influx activates adenylyl cyclase 8 for sustained insulin secretion in rat pancreatic beta cells. Diabetologia. 2015 Feb;58(2):324-33. 
 
Ø  Kang X, Xu H, Teng S, Zhang X, Deng Z, Zhou L, Zuo P, Liu B, Liu B, Wu Q, Wang L, Hu M, Dou H, Liu W, Zhu F, Li Q, Guo S, Gu J, Lei Q, Lü J, Mu Y, Jin M, Wang S, Jiang W, Liu K, Wang C, Li W, Zhang K, Zhou Z. Dopamine release from transplanted neural stem cells in Parkinsonian rat striatum in vivo. Proc Natl Acad Sci U S A. 2014 Nov 4;111(44):15804-9. 
 
Ø  Shang S, Wang C, Liu B, Wu Q, Zhang Q, Liu W, Zheng L, Xu H, Kang X, Zhang X, Wang Y, Zheng H, Wang S, Xiong W, Liu T, Zhou Z. Extracellular Ca²⁺ per se inhibits quantal size of catecholamine release in adrenal slice chromaffin cells. Cell Calcium. 2014 Sep;56(3):202-7. 
 
Ø  Wang L, Zhang X, Xu H, Zhou L, Jiao R, Liu W, Zhu F, Kang X, Liu B, Teng S, Wu Q, Li M, Dou H, Zuo P, Wang C, Wang S, Zhou Z. Temporal components of cholinergic terminal to dopaminergic terminal transmission in dorsal striatum slices of mice. J Physiol. 2014 Aug 15;592(16):3559-76. 
 
Ø  Wang L, Shang S, Kang X, Teng S, Zhu F, Liu B, Wu Q, Li M, Liu W, Xu H, Zhou L, Jiao R, Dou H, Zuo P, Zhang X, Zheng L, Wang S, Wang C, Zhou Z. Modulation of dopamine release in the striatum by physiologically relevant levels of nicotine. Nat Commun. 2014 May 21;5:3925. 
 
Ø  Zheng L, Wang C, Shang S, Zhang X, Wang Y, Wu Q, Hu M, Chai Z, Wu X, Zheng H, Zhang C, Wang L, Xiong W, Zhou Z. Real-time endocytosis imaging as a rapid assay of ligand-GPCR binding in single cells. Am J Physiol Cell Physiol. 2013 Oct 1;305(7):C751-60. 
 
Ø  Zhang B, Zhang X, Luo P, Huang W, Zhu F, Liu T, Du Y, Wu Q, Lü J, Xiu Y, Liu L, Huang H, Guo S, Zheng H, Zhang C, Zhou Z. Action potential-triggered somatic exocytosis in mesencephalic trigeminal nucleus neurons in rat brain slices. J Physiol. 2012 Feb 15;590(4):753-62.