病原感染致病与疫苗研发研究组

Laboratory of Pathogenic Infection and Vaccine Development

发表论文
1.


2023

1.     Giri BR, Li S, Cheng G. Exogenous modification of EL-4 T cell extracellular vesicles with miR-155 induce macrophage into M1-type polarization. Drug Deliv Transl Res. 2023 Oct 10. doi: 10.1007/s13346-023-01442-4.

2.     Liu J, Wang X, Sheng F, Giri BR, Li S, Xia T, Li X, Cheng G. Metagenomic sequencing for identifying pathogen-specific circulating DNAs and development of diagnostic methods for schistosomiasis. iScience. 2023 Jul 27;26(9):107495. doi: 10.1016/j.isci.2023.107495.

3.     Pakharukova MY, Savina E, Ponomarev DV, Gubanova NV, Zaparina O, Zakirova EG, Cheng G, Tikhonova OV, Mordvinov VA. Proteomic characterization of Opisthorchis felineus exosome-like vesicles and their uptake by human cholangiocytes. J Proteomics. 2023 Jul 15;283-284:104927.

4.     Zhang M, Huang Y, Zou J, Yang Y, Yao Y, Cheng G*, Yang Y*. Advanced Oxidation Nanoprocessing Boosts Immunogenicity of Whole Tumor Cells. Adv Sci (Weinh). 2023 May 21:e2302250.

5.     Giri BR, Cheng G*. Editorial: Roles of non-coding RNAs in infectious diseases - volume II. Front Cell Infect Microbiol. 2023 Apr 25;13:1202616.

 

2022

1.     Giri BR, Li S, Fang C, Qiu L, Yan S, Pakharukova MY, Cheng G*. Dynamic miRNA profile of host T cells during early hepatic stages of Schistosoma japonicum infection. Front Immunol. 2022 Sep 2;13:911139.

2.     Giri BR, Fang C, Cheng G*. Genome-wide identification of circular RNAs in adult Schistosoma japonicum. Int J Parasitol. 2022 Aug;52(9):629-636.

3.     Li S, Giri BR, Liu J, He X, Cai P, Jing Z, Cheng G*. Characterization of MicroRNA Cargo of Extracellular Vesicles Isolated From the Plasma of Schistosoma japonicum-Infected Mice. Front Cell Infect Microbiol. 2022 Feb 28;12:803242.


2021

1.     Zaparina OG, Rakhmetova AS, Kolosova NG, Cheng G, Mordvinov VA, Pakharukova MY. Antioxidants resveratrol and SkQ1 attenuate praziquantel adverse effects on the liver in Opisthorchis felineus infected hamsters. Acta Trop. 2021 May 9:105954.

2.     Qadeer A, Giri BR, Ullah H, Cheng G*. Transcriptional profiles of genes potentially involved in extracellular vesicle biogenesis in Schistosoma japonicum. Acta Trop. 2021 May;217:105851.


2020

1.     Xia T, Giri BR, Liu J, Du P, Li X, Li X, Li S, Cheng G*. RNA sequencing analysis of altered expression of long noncoding RNAs associated with Schistosoma japonicum infection in the murine liver and spleen. Parasit Vectors. 2020 Dec 1;13(1):601.

2.     Du P, Giri BR, Liu J, Xia T, Grevelding CG, Cheng G*. Proteomic and deep sequencing analysis of extracellular vesicles isolated from adult male and female Schistosoma japonicum. PLoS Negl Trop Dis. 2020 Sep 28;14(9):e0008618.

3.     Liu J, Li H, Xia T, Du P, Giri B, Li X, Li X, Cheng G*. Identification of Schistosoma japonicum GSK3beta interacting partners by yeast two-hybrid screening and its role in parasite survival. Parasitol Res. 2020 Jul;119(7):2217-2226.

4.     Chen Y, Giri BR, Li X, He X, Jing Z, Cheng G*. Preliminary evaluation of the diagnostic potential of Schistosoma japonicum extracellular vesicle proteins for Schistosomiasis japonica. Acta Trop. 2020 Jan;201:105184.


2019

1.     Giri BR, Cheng G*. Host miR-148 regulates a macrophage-mediated immune response during Schistosoma japonicum infection. Int J Parasitol. 2019 Dec;49(13-14):993-997.

2.     Liu J, Zhu L, Wang J, Qiu L, Chen Y, Davis RE, Cheng G*. Schistosoma japonicum extracellular vesicle miRNA cargo regulates host macrophage functions facilitating parasitism. PLoS Pathog. 2019 June. doi.org/10.1371/journal.ppat.1007817.

3.     Giri BR, Cheng G*. MicroRNAs, T cell immunity and immunotherapy. Future Medicinal Chemistry. 2019 Aug;11(16):2043-2045.

4.     Giri BR, Mahato RI, Cheng G*. Roles of microRNAs in T cell immunity: Implications for strategy development against infectious diseases. Med Res Rev. 2019 Mar;39(2):706-732.

5.     Liu J, Giri BR, Chen Y, Cheng G*. 14-3-3 protein and ubiquitin C acting as SjIAP interaction partners facilitate tegumental integrity in Schistosoma japonicum. Int J Parasitol. 2019 Apr;49(5):355-364.


2018

1.     Liu J, Giri BR, Chen Y, Luo R, Xia T, Grevelding CG, Cheng G*. Schistosoma japonicum IAP and Teg20 safeguard tegumental integrity by inhibiting cellular apoptosis. PLoS Negl Trop Dis. 2018 Jul 25;12(7):e0006654.

2.     Wang L, Giri BR, Chen Y, Xia T, Liu J, Li H, Li J, Cheng G*. Molecular characterization, expression profile, and preliminary evaluation of diagnostic potential of CD63 in Schistosoma japonicum. Parasitol Res. 2018 Nov;117(11):3625-3631.

3.     Giri BR, Li H, Chen Y, Cheng G*. Preliminary evaluation of neoblast-like stem cell factor and transcript expression profiles in Schistosoma japonicum. Acta Trop. 2018 Nov;187:57-64.

4.     Liu J, Zhu L, Wang L, Chen Y, Giri BR, Li J, Cheng G*. Isolation and Characterization of Extracellular Vesicles from Adult Schistosoma japonicum. J Vis Exp. 2018 May 22;(135). doi: 10.3791/57514.

5.     Giri BR, Ye J, Chen Y, Wei C*, Cheng G*. In silico analysis of endogenous siRNAs associated transposable elements and NATs in Schistosoma japonicum reveals their putative roles during reproductive development. Parasitol Res. 2018 May;117(5):1549-1558.


2017年及以前

1.     Giri BR, Du X, Xia T, Chen Y, Li H, Cheng G*. Molecular characterization and expression profile of nanos in Schistosoma japonicum and its influence on the expression several mammalian stem cell factors. Parasitol Res. 2017 Jul;116(7):1947-1954.

2.     Riaz F, Cheng G*. Exosome-like vesicles of helminths: implication of pathogenesis and vaccine development. Ann Transl Med. 2017 Apr;5(7):175. doi: 10.21037/atm.2017.03.45.

3.     Zhu L, Zhao J, Wang J, Hu C, Peng J, Luo R, Zhou C, Liu J, Lin J, Jin Y, Davis RE*, Cheng G*. MicroRNAs Are Involved in the Regulation of Ovary Development in the Pathogenic Blood Fluke Schistosoma japonicum. PLoS Pathog. 2016 Feb 12;12(2):e1005423.

4.     Zhu L, Liu J, Dao J, Lu K, Li H, Gu H, Liu J, Feng X, Cheng G*. Molecular characterization of S. japonicum exosome-like vesicles reveals their regulatory roles in parasite-host interactions. Sci Rep. 2016 May 13;6:25885.

5.     Cheng G*. Circulating miRNAs: Roles in cancer diagnosis, prognosis and therapy. Adv Drug Deliv Rev. 2015 Jan;81:75-93.

6.     Zhu L, Dao J, Du X, Li H, Lu K, Liu J, Cheng G*. Altered levels of circulating miRNAs are associated Schistosoma japonicum infection in mice. Parasit Vectors. 2015 Apr 1;8:196.

7.     Zhu L, Liu J, Cheng G*. Role of microRNAs in schistosomes and schistosomiasis. Front Cell Infect Microbiol. 2014 Nov 11;4:165. doi: 10.3389/fcimb.2014.00165.

8.     Hu, Zhu l, Luo R, Dao J, Zhao J, Shi Y, Li H, Lu K, Feng X, Lin J, Liu J, Cheng G*. Evaluation of protective immune response in mice by vaccination the recombinant adenovirus for expressing Schistosoma japonicum inhibitor apoptosis protein. Parasitol Res. 2014, 113(11):4261-9.

9.     Dao J, Zhu L, Luo R, Hu C, Wang Y, Li H, Lu K, Liu J, Lin J, Cheng G*. Molecular characterization of SjBIRP, another apoptosis inhibitor, from Schistosoma japonicum. Parasitol Res. 2014, 113(11):4065-71.

10.   He X, Jing Z*, Cheng G*. MicroRNAs: new regulators of Toll-like receptor signalling pathways. Biomed Res Int. 2014: 945169. doi: 10.1155/2014/945169.

11.   Cheng G*, Lin J. Parasitic helminths: a useful resource for inflammatory and autoimmune therapy. J Bioanal Biomed. 2013, 5: 075-076.

12.   Cheng G*, Luo R, Hu C, Cao J, Jin Y. Deep sequencing-based identification of pathogen-specific microRNAs in the plasma of rabbits infected with Schistosoma japonicum. Parasitology. 2013 Aug 13:1-11.

13.   Cheng G*, Luo R, Hu C, Lin J, Bai Z, Zhang B, Wang H*. TiO2-based phosphoproteomic analysis of schistosomes: characterization of phosphorylated proteins in the different stages and sex of Schistosoma japonicum. J Proteome Res. 2013 Feb 1;12(2):729-42.

14.   Luo R, Zhou C, Shi Y, Zhao J, Cheng G*. Molecular characterization of a cytokine-induced apoptosis inhibitor from Schistosoma japonicum. Parasitol Res. 2012 Dec;111(6):2317-24.

15.   Cheng G* and Jin YX. microRNAs: Potentially Important Regulators for Schistosome Development and Therapeutic Targets against Schistosomiasis. Parasitology. 2012 Apr;139(5):669-79.

16.   Luo R, Zhou C, Lin J, Yang D, Shi Y, Cheng G*. Identification of in vivo protein phosphorylation sites in human pathogen Schistosoma japonicum by a phosphoproteomic approach. J Proteomics. 2012, 75(3):868-77.

17.   Chen J, Yang Y, Guo S, Peng J, Liu Z, Li J, Lin J*, Cheng G*. Molecular cloning and expression profiles of Argonaute proteins in Schistosoma japonicum. Parasitol Res. 2010;107(4):889-99.

18.   Peng J, Yang Y, Feng X, Cheng G*, Lin J*. Molecular characterizations of an inhibitor of apoptosis from Schistosoma japonicum. Parasitol Res. 2010;106(4):967-76.

19.   Cheng G#, Fu Z#, Lin J, Shi Y, Zhou Y, Jin Y, Cai Y. In vitro and in vivo evaluation of small interference RNA-mediated gynaecophoral canal protein silencing in Schistosoma japonicum. J Gene Med. 2009;11(5):412-21. (#co-first author)

20.   Cheng G, Zhu L, Mahato RI. Caspase-3 gene silencing for inhibiting apoptosis in insulinoma cells and human islets. Mol Pharm. 2008;5(6):1093-102.

21.   Cheng G, Davis RE. An improved and secreted luciferase reporter for schistosomes. Mol Biochem Parasitol. 2007;155(2):167-71.

22.   Cheng G#, Cohen L#, Mikhli C, Jankowska-Anyszka M, Stepinski J, Darzynkiewicz E, Davis RE. In vivo translation and stability of trans-spliced mRNAs in nematode embryos. Mol Biochem Parasitol. 2007;153(2):95-106. (#co-first author)

23.   Cheng G, Cohen L, Ndegwa D, Davis RE. The flatworm spliced leader 3'-terminal AUG as a translation initiator methionine. J Biol Chem. 2006 13;281(2):733-43.

24.   Cheng GF, Lin JJ, Shi Y, Jin YX, Fu ZQ, Jin YM, Zhou YC, Cai YM. Dose-dependent inhibition of gynecophoral canal protein gene expression in vitro in the schistosome (Schistosoma japonicum) by RNA interference. Acta Biochim Biophys Sin. 2005;37(6):386-90.

25.   Cheng GF, Lin JJ, Feng XG, Fu ZQ, Jin YM, Yuan CX, Zhou YC, Cai YM. Proteomic analysis of differentially expressed proteins between the male and female worm of Schistosoma japonicum after pairing. Proteomics. 2005;5(2):511-21.

 



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