真菌感染与分子免疫研究组

Laboratory of Fungi Infection and Molecular Immunity

研究成果
1.

Zhu LL, Zhao XQ, Jiang C, You Y, Chen XP, Jiang YY, Jia XM*, Lin X*. C-Type Lectin Receptors Dectin-3 and Dectin-2 Form a Heterodimeric Pattern-Recognition Receptor for Host Defense against Fungal Infection. Immunity, 2013, 39(2): 324–334. (*通讯作者,IF=43.474); 

2.

Xu X; Xu JF; Zheng G; Lu HW; Duan JL; Rui W; Guan JH; Cheng LQ; Yang DD; Wang MC; Lv QZ; Li JX; Zhao X; Chen CX; Shi P; Jia XM*; Lin X*, CARD9S12N facilitates the production of IL-5 by alveolar macrophages for the induction of type 2 immune responses. Nat Immunol. 2018 Jun;19(6):547-560. (*通讯作者,IF:31.250

3.

Lv QZ, Li DD, Han H, Yang YH, Duan JL, Ma HH, Yu Y, Chen JY, Jiang YY*Jia XM*. Priming with FLO8-deficient Candida albicans induces Th1-biased protective immunity against lethal polymicrobial sepsis. Cell Mol Immunol. 2021 Aug;18(8):2010-2023.(*通讯作者,IF:22.096

4.

Li YN, Wang ZW, Li F, Zhou LH, Jiang YS, Yu Y, Ma HH, Zhu LP, Qu JM*, Jia XM*. Inhibition of myeloid-derived suppressor cell arginase-1 production enhances T-cell-based immunotherapy against Cryptococcus neoformans infection. Nat Commun. 2022 Jul 14;13(1):4074. (*通讯作者,IF:17.694)

5.

Zhu LL, Luo TM, Xu X, Guo YH, Zhao XQ, Tang B, Jiang YY, Lin X*, Jia XM*.. E3 ubiquitin ligase Cbl-b negatively regulates C-type lectin receptor–mediated antifungal innate immunity. J Exp Med. 2016;213(8):1555-70. (*通讯作者,IF=17.579);

6.

Jia XM*, Tang B, Zhu LL, Zhao XQ, Gorjestani S, Hsu YS, Xu GT, Lin X*. CARD9 mediates Dectin-1–induced ERK activation by linking Ras-GRF1 to H-Ras for antifungal immunity. J Exp Med. 2014; 211(11):2307-21. (*通讯作者,IF=17.579); 

7.

Duan JL, He HQ, Yu Y, Liu T, Ma SJ, Li F, Jiang YS, Lin X, Li DD, Lv QZ, Ma HH, Jia XM*. E3 ligase c-Cbl regulates intestinal inflammation through suppressing fungi-induced noncanonical NF-κB activation. Sci Adv. 2021 May 7(19): eabe5171. (*通讯作者,IF:14.957).

8.

Wang W, Ding CL, Wu MX, Guo W, Hu R, Liu Y, Qi ZT, Jia XM*. RAI16 maintains intestinal homeostasis and inhibits NLRP3-dependent IL-18/CXCL16-induced colitis and the progression of colitis-associated colorectal cancer. Clin Transl Med. 2022 Aug;12(8):e993. (*通讯作者,IF:8.554)

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